Prion diseases (also referred to as transmissible spongiform encephalopathies, or TSEs) are a group of progressive, untreatable, and fatal neurodegenerative conditions affecting both humans and animals. Generally, these conditions are characterized by long incubation periods (usually between 5 to 20 years), disruption in the normal tissue structure (resulting in holes and vacuole formation in the neurons), and the absence of an inflammatory response.
What is the Link between Protein Folding and Prion Disease?
Topics: Protein Purification, Molecular Biology, Western Blotting, Protein Electrophoresis, Cytotoxicity Assays, Sample Clean Up, Protein Concentration, Protein Fractionation, Protein Labeling, Protein Extraction, Buffers & Chemicals
Exploring the Genetic Causes of ALS (Lou Gehrig's Disease)
Despite the advances in modern medicine, no one knows for sure what causes amyotrophic lateral sclerosis (ALS), also called Lou Gehrig’s disease. Scientists can only theorize and speculate as to what causes it, but they still don’t have a conclusive answer to this question.
Topics: Protein Purification, Western Blotting, Assay Development (ELISA), Sample Clean Up, Protein Concentration, Protein Extraction, Protein Detection
Topics: Protein Purification, Molecular Biology, Assay Development (ELISA), Sample Clean Up
Subcellular Fractionation: ‘Exploring cells through centrifugation'
Topics: Protein Purification