The Protein Man's Blog | A Discussion of Protein Research

Whenever you work in the histology lab, there is a great chance that you’ll be using some type of fixatives before you can proceed with your experiment. By definition, fixation is the process of preserving biological tissues by terminating any biochemical reactions thereby preventing autolysis and putrefaction. It also preserves the integrity and morphology of the sample by inhibiting bacterial and fungal growth.

Biotechnology is the fastest growing occupation among industries, expected to grow 11% by 2022. Teaching biotechnology through the applications of biology, chemistry, engineering research, and manufacturing techniques is critical to the future of creating products and services that improve the quality of human life.

The stability of proteins is crucial in many in vitro protein studies and is considered a major requirement in functional studies involving native and recombinant proteins. Thus, understanding protein stability and preserving the native conformation and normal functions of your protein of interest can be very helpful when working with your protein of interest.

In mass spectrometry-based proteomics, nothing comes close to trypsin in breaking down protein mixtures into peptide fragments.  In fact, protein researchers consider trypsin as the runaway winner when it comes to protease activity and specificity – and there are a lot of good reasons why they do.