Genome editing used to be a long, laborious, and expensive process that, for quite a long time, you’d have been forgiven for thinking only worked on mice. In the earlier days, making a single genomic modification on a target organism could take a year or so and may have cost up to several hundreds of thousands of dollars to complete. Thankfully, these limitations were addressed with the development of powerful alternative bioengineering technologies, namely ZFN, TALENs, and CRISPR.
CRISPR, ZFNs, TALENs: Differences Between Bioengineering Technologies
Posted by
The Protein Man on May 5, 2020 2:09:00 PM
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Topics: Molecular Biology
Antibody Purification by Affinity Chromatography
Posted by
The Protein Man on Apr 28, 2020 2:30:00 PM
The availability of purified antibodies is essential to various applications. While there are various methods of purification, affinity chromatography is the most popular antibody purification technique.
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Topics: Protein Purification, Antibody Production
How the ACE2 Receptor Enables SARS and COVID-19
Posted by
The Protein Man on Apr 21, 2020 11:22:00 AM
With more than one million cases in 208 countries and territories around the world, the scientific and medical communities are on a race against time to find a viable prevention and treatment plan for the novel coronavirus (SARS-CoV-2) and its associated disease, COVID-19, which has already claimed tens of thousands of lives to date. This challenge has led them to focus on how the virus breaks into human cells.
How Does the Coronavirus Infect Target Cells?
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Topics: Molecular Biology, Sample Clean Up
Why Do I Need a Cocktail for Proteases and Phosphatases?
Posted by
The Protein Man on Apr 14, 2020 2:30:00 PM
Protease and phosphatase inhibitor cocktails are essential to most cell lysis and protein extraction procedures. The inhibitors protect protein samples from degradation and preserve their phosphorylation state.
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Topics: Protease Inhibitors