The Protein Man's Blog | A Discussion of Protein Research

Proteinase K is a serine protease, the presence of a catalytic triad characterizes serine proteases, the catalytic triad is a cluster of three amino acids that make the catalytic center and consists of serine, aspartic acid, and histidine amino acids, which can often vary but all of these enzymes have a nucleophile serine and the same catalytic mechanism. Proteinase K has a catalytic triad consisting of Ser 224, His 69, and Asp 39. The substrate recognition sites are made up of peptide chains, 99-104 and 132-136.

Alzheimer’s disease (AD) is a progressive neurologic disorder that leads to the death of brain cells. People with this condition usually exhibit mild memory loss, impaired judgment, and vision (spatial) issues during the initial stages, but the symptoms gradually worsen over time.